Comparison of the Pain Levels of Single-Dose Premedication With Piroxicam and Prednisolone on Pos… (NCT07281807) | Clinical Trial Compass
Not Yet RecruitingPhase 4
Comparison of the Pain Levels of Single-Dose Premedication With Piroxicam and Prednisolone on Post-Endodontic Pain in Single-Visit Root Canal Treatment of Premolars
60 participantsStarted 2026-01-01
Plain-language summary
To compare the post operative mean pain scores by administering single-dose preoperative piroxicam and prednisolone in patients of irreversible pulpitis with symptomatic apical periodontitis.
Who can participate
Age range18 Years – 40 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Healthy patient ranging between 18-40 years
* Having at least one premolar with diagnosis of symptomatic irreversible pulpitis according to history, examination and radiographs.
* Teeth having mature apex confirmed by periapical radiographs.
Exclusion Criteria:
* History of systemic disorders including HIV, Hepatitis
* Pregnancy (As per Medical record/ Verbally)
* Patient using medication such as analgesics or anti-inflammatory drugs
* Patient allergic to lignocaine, piroxicam and prednisolone
* Tooth not suitable for restoration
* Periodontal probing depth ≥ 4mm
* Retreatment cases
* Patients having calcified canals assessed by radiographic findings