RecruitingNot Applicable

IOP Reduction in Pigmentary Glaucoma Using DSLT

United States45 participantsStarted 2026-03-19

Plain-language summary

This study is a single-site, single-arm, prospective, observational study of IOP reduction after DSLT. Subjects will be assessed up to 12 months post-operatively. Clinical evaluations will include IOP and number of glaucoma medications.

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients with pigmentary dispersion syndrome with elevated IOP or mild to moderate (based on AAO Preferred Practice Program criteria) pigmentary glaucoma with glaucomatous optic neuropathy and corresponding visual field/RNFL loss. * Treatment naive, or washed out IOP ranging from ≥18-34 mmHg * Central corneal thickness (CCT) 480-600 µm * Able to complete medication washout and follow-up Exclusion Criteria: * Prior incisional glaucoma surgery or glaucoma-related procedures in the study eye * Prior laser trabeculoplasty \<3 years * Prior intraocular surgery and refractive surgery, except for cataract surgery unless greater than 2 years * Patients anticipating cataract surgery within the follow-up period * History of ocular inflammation and infection * All other secondary glaucoma including exfoliative * Patients unable to have DSLT treatment

What they're measuring

Mean washed-out IOP change post-DSLT compared to washed-out baseline IOP

Timeframe: 6 months post-DSLT

Trial details

NCT IDNCT07281391

SponsorMann Eye Institute

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-04-01

Contact for this trial

Melissa Wright

713-580-2500 Melissa.Wright@manneye.com

View on ClinicalTrials.gov More Pigmentary Dispersion Syndrome trials