Not Yet RecruitingNot Applicable

Mortality and Muscle Mass Loss in Critically Ill Patients.

Czechia386 participantsStarted 2025-12-15

Plain-language summary

The aim of the study is to monitor changes in muscle mass in critically ill patients and to verify whether a decrease in muscle mass of ≥10% during the first 7 days of hospitalization is associated with increased 28-day mortality. We will be used ultrasoud for measurement the rectus femoris cross sectional area.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age ≥18 years * mechanical ventilation expected for at least 48 hours Exclusion Criteria: * Clinical Frailty Score above 7 prior admission * Neuromuscular disease in previous medical history * Amputated lower extremities * Trauma of lower extremities involving tights * Conditions affecting the nervous system with involvement of the thigh muscle * Inability to cooperate during ultrasound examination * Inability to perform ultrasound examination on day 7 9\. Inability to perform ultrasound examination on day 7

What they're measuring

Relationship between muscle loss and 28 day mortality

Timeframe: 28 days after enrollment

Trial details

NCT IDNCT07280039

SponsorBrno University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-12-15

Contact for this trial

Jana Fialová, M.D.

+42053322305 1149@fnbrno.cz

View on ClinicalTrials.gov More Mortality trials