CompletedPhase 2/3

Implications of Post-Operative Irrigation Fluid's Osmolarity on the Recurrence of Non-Muscle Invasive Bladder Cancer Following Transurethral Resection

Egypt150 participantsStarted 2024-10-01

Plain-language summary

This randomized controlled trial will evaluate the efficacy of three bladder irrigation solutions - distilled water (DW), normal saline (NS), and hypertonic saline (HS) - as continuous bladder irrigation (CBI) following transurethral resection of non-muscle invasive bladder cancer (NMIBC). Short term (6 months) recurrence and progression free survival are mainly evaluated.

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients of non-muscle invasive urinary bladder urothelial carcinoma amenable for complete resection Exclusion Criteria: * Patients with post-operative complications that need prolonged irrigation. * Patient who underwent incomplete resection during TURBT. * When large bladder perforation was suspected during TURBT. * Patients with chronic kidney disease. * Muscle invasive disease

What they're measuring

Risk of Recurrence

Timeframe: 6 months

Risk of progression of bladder cancer

Timeframe: 6 months

Trial details

NCT IDNCT07279792

SponsorAin Shams University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-01

View on ClinicalTrials.gov More Bladder (Urothelial, Transitional Cell) Cancer trials