Not Yet RecruitingNot Applicable

The Effect of Caffeine Therapy in Cardiovascular Stability in Preterm Neonates at Assiut University Children Hospital NICU

40 participantsStarted 2026-06-30

Plain-language summary

Preterm neonates younger than 37 weeks gestational age receiving caffeine therapy for apnea of prematurity in a NICU setting.

Who can participate

Age range37 Weeks

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Preterm neonates with gestational age \<37 weeks * Receiving caffeine therapy for apnea of prematurity * Hemodynamically stable before caffeine initiation Exclusion Criteria: * Presence of major congenital anomalies * Use of vasopressors at baseline * Severe intraventricular hemorrhage (Grade III-IV)

What they're measuring

Change in mean arterial blood pressure after caffeine therapy in preterm neonates.

Timeframe: Baseline before caffeine administration and at 1, 6, 12, and 24 hours after caffeine dose.

Change in perfusion index after caffeine therapy in preterm neonates.

Timeframe: Baseline before caffeine administration and at 1, 6, 12, and 24 hours after caffeine dose.

Change in heart rate after caffeine therapy in preterm neonates.

Timeframe: Baseline before caffeine administration and at 1, 6, 12, and 24 hours after caffeine dose.

Trial details

NCT IDNCT07274969

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-08-30

View on ClinicalTrials.gov More Preterm Neonates trials