Interrupted vs Subcuticular Sutures With Drain in Open Appendectomy (NCT07274878) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Interrupted vs Subcuticular Sutures With Drain in Open Appendectomy
100 participantsStarted 2025-12-01
Plain-language summary
The primary aim of this study is to compare wound outcomes between two closure strategies after open appendectomy:
1. Simple interrupted skin sutures (standard method), versus
2. Subcuticular (intradermal) skin suture combined with a subcutaneous closed suction drain.
Specifically, the study aims to
* Determine whether the combined subcuticular closure with drain reduces the incidence of superficial surgical- site infection (SSI) within 30 days compared with interrupted sutures.
* Evaluate the effect of both techniques on secondary outcomes, including seroma or abscess formation, wound dehiscence, post-operative pain, cosmetic appearance of the scar, length of hospital stay, and drain-related adverse events.
Who can participate
Age range
14 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥ 14 years (or per local ethics), undergoing open appendectomy for acute appendicitis (elective not included).
* Skin incision for open appendectomy (McBurney/Gridiron or Lanz).
* Patient (or legal guardian) able and willing to provide informed consent.
Exclusion Criteria:
* Laparoscopic appendectomy or conversion to laparoscopic approach.
* Previous abdominal surgery at the same site (risk of altered wound healing).
* Pre-existing skin infection at the surgical site.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of superficial surgical-site infection (SSI)