Effects of Ankle Evertor Fatigue on Perturbed Gait (NCT07273097) | Clinical Trial Compass
RecruitingNot Applicable
Effects of Ankle Evertor Fatigue on Perturbed Gait
Slovenia40 participantsStarted 2025-05-05
Plain-language summary
This study will investigate the effects of ankle evertor muscle fatigue on gait stability during treadmill walking with mechanical perturbations. Participants will walk at two speeds (0.4 m/s and 1.0 m/s) while random medial and lateral perturbations (\<10% body weight) are applied to the pelvis. Surface EMG from ankle muscles and center of pressure (COP)-based gait parameters (e.g., step length, step width, single support duration, COP trajectory) will be analyzed before and immediately after an isotonic fatigue protocol of the ankle evertors.
Who can participate
Age range
18 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria for the healthy control group (no CAI):
* Age between 18 and 45 years,
* No history of injuries or surgical procedures to the lower limbs,
* No peripheral or central neurological impairments.
Inclusion criteria for the chronic ankle instability (CAI) group:
* Age between 18 and 45 years,
* No history of major surgical procedures on the lower limbs
* No peripheral or central neurological impairments,
* Diagnosed chronic ankle instability:
* First ankle sprain occurred at least one year prior to testing,
* At least three months since the most recent ankle sprain,
* Subjective feeling of ankle instability - CAIT (Cumberland Ankle Instability Tool) score \< 24.
Exclusion criteria for the CAI group:
* Other pathologies of the ankle joint.
* Acute pain
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Surface EMG root mean square (RMS) amplitude of ankle muscles
Timeframe: Baseline (Day 1, prior to fatigue protocol) and immediately post-fatigue (Day 1, within 5 minutes after fatigue protocol).
2
Center of Pressure mediolateral displacement (COPx)
Timeframe: Baseline (Day 1, prior to fatigue protocol) and immediately post-fatigue (Day 1, within 5 minutes after fatigue protocol).