This study aims to investigate the effect of high-intensity interval training (HIIT) on fatigue severity among individuals with chronic stroke. Participants will be randomly assigned to the HIIT group, the moderate-intensity continuous training (MICT) group, or the stretching group (active control). Each group will participate in supervised exercise sessions three times per week over a 12-week period, totaling 36 sessions. Outcome assessments will be conducted at baseline, mid-intervention (week 6), post-intervention (week 12), and follow-up (week 20). The primary outcome will be fatigue severity. Secondary outcomes will include inflammatory biomarkers and additional health-related indicators.
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Eligibility rate (%)
Timeframe: Through study completion, an average of 12 weeks.
Recruitment rate (number of participants per month)
Timeframe: Through study completion, an average of 12 weeks.
Compliance with HIIT (%)
Timeframe: From baseline to week 12
Fidelity to the HIIT protocol (%)
Timeframe: From baseline to week 12
Retention of the intervention (%)
Timeframe: From baseline to week 12
Adverse events (number of events)
Timeframe: From baseline to week 12
Acceptability (qualitative)
Timeframe: At week 12