RecruitingNot Applicable

Research on Anesthesia Depth Control Strategy Based on Continuous and Non-invasive Monitoring of Exhaled Breath

China500 participantsStarted 2024-03-16

Plain-language summary

This study aims to propose a strategy for controlling the depth of anesthesia based on continuous and non-invasive monitoring of exhaled breath: BIS value during intravenous-inhalation combined anesthesia is predicted according to the real-time exhaled concentrations of sevoflurane and propofol, so as to achieve the depth of anesthesia management for patients who cannot use standard BIS. Furthermore, the relationship between anesthetic concentration and depth of anesthesia was analyzed in different subgroups.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age ≥18 years old * ASA I-III * Expected duration of surgery \> 1 hour * Radial artery catheterization was performed * Patients requiring BIS monitoring. Exclusion Criteria: * Patients with contraindications to general anesthesia * mental disorder, unable to answer * long-term use of antiepileptic drugs and psychotropic drugs * pregnant patients * patients refused to participate * the investigator thought that the study was not suitable for inclusion * patients who did not wake up in PACU

What they're measuring

Correlation and consistency analysis between exhaled breath concentrations of two anesthetics and BIS values

Timeframe: 1 day

Establish a 3D drug dose-effect model of the exhaled concentration and BIS value of anesthetics

Timeframe: 1day

Trial details

NCT IDNCT07272044

SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-03-15

Contact for this trial

Fengjiang Zhang

18875213201 zrzfj@edu.cn

View on ClinicalTrials.gov More Anesthesia trials