RecruitingPhase 2

Alii Supplement Study

United States68 participantsStarted 2026-01-12

Plain-language summary

The goal of this clinical trial is to learn if the Alii Supplement can be used to reduce symptoms related to nutritional depletion in hormonal birth control pill users. The main questions it aims to answer are: Does usage of the supplement increase happiness, decrease perceived vulnerability to disease, increase digestive health, decrease mood swings, and increase energy? The investigators will compare the Alii Supplement to a placebo (a capsule that contains no drug) to see if the Alii Supplement works to reduce symptoms associated with nutritional depletion. Participants will: Take the placebo or Alii Supplement everyday for 28 days and visit the research office twice to fill out an online survey comprising of items examining the main outcome measures.

Who can participate

Age range18 Years – 25 Years

SexFEMALE

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Inclusion Criteria: * Participants must be on the hormonal birth control pill as the investigators are testing the effectiveness of a supplement for women who take the hormonal birth control pill * Participants must be willing to complete a follow up survey as this study will be multiple parts * Participants must be willing to take a daily supplement as this study is testing how a supplement influences a variety of psychological outcomes * Participants must be on the hormonal birth control pill for at least six months as participants who have been on the pill for less than 6 months may not be experiencing nutritional depletion yet * If the investigators are able to do so, the investigators will only recruit participants who take the one-month hormonal birth control pill rather than the three month hormonal birth control pill, as the investigators are going to have participants come in after 28 days (day 2 of pack 1 and day 2 of pack 2) and participants on the three-month HBC pill may be on a 21 day cycle. * Participants must have no food or medication allergies that will prevent the participants from safely taking the supplement * Participants must not be taking any vitamins or participant must report willingness to abstain from taking vitamins during the study as individuals who are already taking vitamins may not be experiencing nutritional depletion associated with hormonal birth control * If the investigators have the ability to do so, the investigators will only recruit…

What they're measuring

Change from Baseline in Levels of Perceived Vulnerability to Disease Scale after 1 Month of Drug Usage

Timeframe: From day 1 of supplement usage to the end of treatment at 4 weeks.

Change from Baseline in Levels of Happiness after 1 Month of Drug Usage

Timeframe: From day 1 of supplement usage to the end of treatment at 4 weeks.

Change from Baseline in Levels of Digestive Health after 1 Month of Drug Usage

Timeframe: From day 1 of supplement usage to the end of treatment at 4 weeks.

Change from Baseline in Levels of Mood Swings after 1 Month of Drug Usage

Timeframe: From day 1 of supplement usage to the end of treatment at 4 weeks.

Change from Baseline in Levels of Energy after 1 Month of Drug Usage

Timeframe: From day 1 of supplement usage to the end of treatment at 4 weeks.

Trial details

NCT IDNCT07271316

SponsorTexas Christian University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-04-29

Contact for this trial

Sarah E Hill, PhD

817-257-6424 s.e.hill@tcu.edu

View on ClinicalTrials.gov More Nutrient Deficiency trials