Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration (NCT07269808) | Clinical Trial Compass
Active — Not RecruitingPhase 3
Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration
United States100 participantsStarted 2026-03-03
Plain-language summary
This study is a pragmatic, randomized controlled pilot trial comparing remimazolam with propofol for endoscopic procedures, designed to assess the feasibility and clinical outcomes associated with implementing a pragmatic randomized trial of sedation practices in the endoscopy setting.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged 18 years of age or older
* Planned endoscopic procedure
* American Society of Anesthesiologists (ASA) Physical Status I to III
Exclusion Criteria:
* Planned tracheal intubation
* Procedure length anticipated to exceed 45 minutes
* Previously participated in the trial
* Pregnant (defined as a positive test using pre-procedural clinical testing performed as part of their routine care) or breastfeeding
* Allergy or hypersensitivity to one of the study medications
* Blind, deaf, or unable to communicate in English
* Co-enrollment in other interventional studies that, in the opinion of the site investigator and/or their delegate, might interfere with study participation, collection, or interpretation of the study data
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of Patients Meeting Inclusion/Exclusion Criteria
Timeframe: From initiation of screening through end of study enrollment period.
2
Number of Patients Consented
Timeframe: From initiation of recruitment through end of study enrollment period.
3
Number of Patients Receiving the Randomized Intervention Per Protocol
Timeframe: From randomization through completion of the endoscopic procedure.
4
Number of Completed Questionnaires
Timeframe: At the end of the procedure and at the immediate post-procedure assessment.