Ultrasound-guided vs Conventional Intraarticular Injection of Hyaluronic Acid for Management of T… (NCT07266714) | Clinical Trial Compass
CompletedNot Applicable
Ultrasound-guided vs Conventional Intraarticular Injection of Hyaluronic Acid for Management of Temporomandibular Joint Internal Derangement
Egypt40 participantsStarted 2024-09-01
Plain-language summary
The aim of the study will be to evaluate the clinical efficacy of using ultrasound guidance during intra-articular injection of hyaluronic acid in the management of patients with TMJ internal derangement.
Who can participate
Age range
18 Years – 50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Patients that will be diagnosed disc displacement confirmed clinically and by Magnetic Resonance Imaging (MRI).
. Patient not responding to conservative therapy
. Patients age must be (18 - 50).
. Patients having painful joint, clicking sound, with or without limited mouth opening.
. Patient's ability and desire to complete the treatment protocol and follow-up visits.
Exclusion criteria
. Patient with an inflammatory or connective tissue disease
. Patient with previous invasive TMJ surgical procedure.
. Patient with Neurologic disorders
. History of injection of any substance into the target TMJ during previous 6 months.
. Patient with a history of bony adhesion.
. Malignant disease in the head and neck region.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Pain (Visual Analogue Scale)
Timeframe: preoperative and postoerative after 1 week, 3 month and 6 month
2
Clicking sound
Timeframe: preoperative and postoerative after 1 week, 3 month and 6 month
3
Maximum inter-incisal opening (MIO)
Timeframe: preoperative and postoerative after 1 week, 3 month and 6 month
4
Range of lateral mandibular excursions
Timeframe: preoperative and postoerative after 1 week, 3 month and 6 month