Not Yet RecruitingNot Applicable

Zinc Oxide-Ozonated Olive Oil vs Metapex in Primary Anterior Teeth

Egypt52 participantsStarted 2025-12-01

Plain-language summary

This randomized clinical trial compares zinc oxide-ozonated olive oil and Metapex as root canal filling materials in primary anterior teeth of children aged 3-5 years. The study aims to evaluate their clinical and radiographic success over 12 months.Clinical evaluation includes pain, swelling, and mobility; radiographic evaluation includes periapical healing and resorption.

Who can participate

Age range3 Years – 5 Years

SexALL

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Inclusion criteria

✓. Children aged 3-5 years.
✓. Primary anterior teeth requiring root canal treatment due to irreversible pulpitis.
✓. Cooperative behavior child.
✓. Parents provided written informed consent. -

Exclusion criteria

✕. Medically compromised children.
✕. Tooth with advanced root resorption.
✕. Non-restorable crown structures.
✕. Tooth with abscess or fistula.
✕. Allergies or hypersensitivity to any of the materials used e.g., zinc oxide, olive oil, or calcium hydroxide and Idoform (components of Metapex).
✕. Unable to attend follow-up visits.

What they're measuring

Clinical success: absence of pain, swelling, tenderness, or mobility

Timeframe: 12 month intervals T0: 0 T1: 3month T2: 6month T3: 9month T4: 12month

Trial details

NCT IDNCT07265089

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-01

Contact for this trial

Raheeq Babiker Ibrahim Babiker, Master degree

+201145501017 raheeq.babiker@dentistry.cu.edu.eg

View on ClinicalTrials.gov More Carious Anterior Teeth trials