The Effect of a Single Training Session on Changes in Inflammatory, Hormonal, and Metabolic Marke… (NCT07264751) | Clinical Trial Compass
CompletedNot Applicable
The Effect of a Single Training Session on Changes in Inflammatory, Hormonal, and Metabolic Markers in Athletes
Poland5 participantsStarted 2014-02
Plain-language summary
The study aims to assess the acute response of wrestlers to a single training session. Short-term changes in inflammatory, hormonal, and metabolic markers are analyzed to assess fatigue development and recovery following intense exercise. Participation in the study involves completing a standard training session and providing blood samples at three time points to assess the physiological response. The results provide a better understanding of the mechanisms underlying adaptation to exercise in competitive wrestlers.
Who can participate
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Currently engaged in regular strength-endurance wrestling training.
* Medically cleared for high-intensity exercise by a sports physician.
* Willingness to participate and provide written informed consent.
* Availability to attend the training session and all blood sampling time points (pre-training, immediately post-training, 24 hours post-training).
Exclusion Criteria:
* Presence of acute or chronic illness that may affect exercise performance or physiological response.
* Recent musculoskeletal injury limiting participation in high-intensity training.
* Use of medications or supplements that may interfere with hormonal, inflammatory, or metabolic markers.
* History of endocrine disorders, adrenal insufficiency, or other conditions affecting catecholamine or cortisol levels.
* Inability or unwillingness to comply with study procedures.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Concentration of high-sensitivity C-reactive protein (hsCRP)
Timeframe: 1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.
2
Concentration of creatine kinase (CK)
Timeframe: 1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.
3
Concentration of tumor necrosis factor-alpha (TNF-α).
Timeframe: 1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.
4
Concentration of interleukin-6 (IL-6).
Timeframe: 1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.
5
Concentration of adrenaline
Timeframe: 1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.
6
Concentration of noradrenaline
Timeframe: 1. Before training (at rest), 2. Immediately after training, 3. 24 hours after exercise.