LA Strain in Predicting Early Complication in STEMI After PPCI (NCT07263282) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
LA Strain in Predicting Early Complication in STEMI After PPCI
Egypt135 participantsStarted 2025-12-01
Plain-language summary
The goal of this observational study To evaluate the predictive value of left atrial strain for in-hospital outcomes in patients with ST-segment elevation myocardial infarction undergoing PPCI. The main questions it aims to answer are:
Is low parameters of left atrial strain associated early complication ? What is the correlation between LA strain parameters and conventional echocardiographic indices of left ventricular systolic and diastolic function ? Is there more affection to LA strain in certain territory over the others ? What is the correlation between LA strain and LA volume index across infarct territories ? Does LA strain Correlate with TAPSE and PASP to evaluate right-heart interactions ?
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults aged ≥18 years.
* Diagnosed with ST-segment elevation myocardial infarction (STEMI) according to current ESC/AHA criteria
* Underwent successful primary percutaneous coronary intervention (PPCI) within 12 hours of symptom onset.
* Sinus rhythm on admission .
* Trans thoracic echocardiography (TTE) performed within 48 hours of admission with adequate image quality for speckle-tracking analysis.
Exclusion Criteria:
* Previous myocardial infarction or prior PCI/CABG.
* Patients known to have atrial fibrillation or other sustained supraventricular arrhythmias.
* Significant valvular heart disease (severe stenosis or regurgitation).
* Congenital heart disease or cardiomyopathy (hypertrophic, dilated, restrictive).
* Poor echocardiographic window preventing LA strain analysis .
* Mechanical complications (e.g., papillary muscle rupture, VSD, free wall rupture).
* Prior cardiac surgery or known structural lesions that preventing reliable LA measurement.
* patient presenting with killip class III or IV from the start
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
the predictive value of left atrial strain for detecting incidence of in-hospital outcomes in patients with ST-segment elevation myocardial infarction undergoing primary PCI.