Median Nerve Decompression for Complex Regional Pain Syndrome: A Clinical Study (NCT07263256) | Clinical Trial Compass
CompletedNot Applicable
Median Nerve Decompression for Complex Regional Pain Syndrome: A Clinical Study
Czechia74 participantsStarted 2014-01
Plain-language summary
This clinical study evaluates the effectiveness of surgical treatment in patients with upper-limb complex regional pain syndrome (CRPS) diagnosed according to the Budapest criteria. Seventy-four patients were assessed between 2014 and 2023. Patients with identifiable structural pathology underwent lesion-specific surgical correction, while those without detectable lesions but with neuropathic nocturnal pain underwent decompression of the median nerve. Pain intensity was measured using the visual analogue scale (VAS) preoperatively, at 10-12 days, and at three months. The study aims to determine the speed and magnitude of pain improvement after targeted surgical intervention.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Diagnosed Complex Regional Pain Syndrome (CRPS) according to Budapest criteria
* Age ≥ 18 years
* Persistent symptoms despite previous conservative treatment
* Ability to understand the study information and provide informed consent
* Ability to adhere to postoperative follow-up
Exclusion Criteria:
* Active local or systemic infection
* Severe uncontrolled psychiatric illness
* Coagulopathy or anticoagulation therapy contraindicating surgery
* Pregnancy
* Previous extensive surgical interventions on the same site interfering with planned procedure
* Inability to comply with follow-up
* Any other condition that, in the opinion of the investigator, makes participation unsafe
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in Pain (VAS Score)
Timeframe: Baseline, 10-12 days post-op, 3 months post-op