This is an international, multicenter, observational study aimed at investigating acute kidney injury requiring renal replacement therapy (AKI-RRT) in Latin American countries. The main questions this study aims to answer are:
* What is the epidemiology, outcomes, and processes of care for patients with AKI-RRT in Latin America?
* How do outcomes differ across different countries in Latin America?
* What factors (demographics, clinical, socioeconomic) influence outcomes in patients with AKI-RRT in Latin America?
The main aims of this study are to:
* Establish a comprehensive database containing clinical, laboratory, treatment, process, and outcome data of patients with AKI-RRT in Latin America
* Describe current epidemiology of AKI-RRT in Latin America
* Compare processes of care and outcomes across different countries in Latin America
* Provide data resources to facilitate and promote clinical research in AKI-RRT
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult patient (≥18) admitted to the ICU
* First ICU admission during current hospitalization
* Diagnosis of acute kidney injury stage 3 according to KDIGO guidelines
* RRT initiated no earlier than 3 days before or no later than 7 days after ICU admission
Exclusion Criteria:
* Transfer from outside hospital with ongoing RRT
* RRT exposure of less than 2 days (if CRRT or PD was provided) or less than 2 HD/SLED sessions
* Kidney failure (ESRD) patients on maintenance dialysis
* Kidney transplant recipients
* Previous or new diagnosis of glomerulonephritis
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
In-hospital mortality
Timeframe: From enrollment to hospital discharge or 90 days (whichever occurs first)