CompletedNot Applicable

Cytokines as Diagnostic Markers of Pulpal Inflammation and Their Impact on the Outcome of Vital Pulp Therapy

Egypt40 participantsStarted 2022-10-01

Plain-language summary

intervention eligible patients with teeth diagnosed with reversible or irreversible pulpits will go for vital pulp therapy and the other group will be patients will go for extraction of caries free teeth for orthodontic reasons, blood samples will be collected from both groups to analyze the level of cytokines IL-8 and IL-10 and it's relation with the success of the pulp therapy

Who can participate

Age range16 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * The age ranges from 16-45 years medically free. * Tooth should be vital on cold testing. * Vital permanent premolar and molar on cold testing, with deep caries, subsequent pulp exposure and bleeding pulp tissue in all canals after complete pulpotomy. * Diagnosis is either reversible or irreversible pulpitis with/ without periapical rarefaction. * The tooth is restorable and free from advanced periodontal disease. * Soft tissues around the tooth are normal with no swelling or sinus tract. Exclusion Criteria: * Patients over 45 years of age. * Patients with clinical symptoms of periradicular inflammation or any periradicular radiographic lesions. * Negative results for cold and electrical pulp testing

What they're measuring

Clinical success

Timeframe: one day, one, four and twelve weeks.

Trial details

NCT IDNCT07261761

SponsorMansoura University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-10-01

View on ClinicalTrials.gov More Reversible Pulpitis trials