Cervical Spine Abnormalities in Down Syndrome (NCT07260136) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Cervical Spine Abnormalities in Down Syndrome
Egypt50 participantsStarted 2025-10-23
Plain-language summary
The study aims to determine the prevalence,clinical presentations and radiographic cervical spine abnormalities associated Down syndrome in children at sohag university hospital
Who can participate
Age range
2 Years – 18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* All patients attending to pediatric inpatient and outpatient clinics aged from 2y up to 18 y
Exclusion Criteria:
* children with other clinical syndromes Children with other neurological disorders (eg. Cerebral palsy , myopathy, neuropathy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Since this study is focused on understanding how common cervical spine problems are in people with Down syndrome and what they look like on imaging, could it help us get a clearer picture of whether my child actually has cervical spine instability that we should be monitoring?
2This trial is listed as 'active, not recruiting,' which means they're no longer enrolling new participants — so is there a similar study or registry we could look into that is still open, or could the findings from this research influence how you approach my child's cervical spine screening?
3Since one of the main goals is to document both clinical presentations and X-ray findings together, does my child currently show any symptoms — like neck pain, unusual head position, or changes in walking — that would already prompt you to order cervical spine imaging regardless of a study?
4Down syndrome guidelines already recommend cervical spine X-rays at certain ages — how does what this study is measuring compare to what you're already doing for my child's routine care, and would the study's findings change anything about our current monitoring plan?
5If this research helps establish better prevalence data for cervical spine abnormalities in Down syndrome, how might that eventually change the screening recommendations we should be following, and when should we expect updated guidance to be available?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Determine the prevalence, clinical presentations and radiographic cervical spine abnormalities associated with Down syndrome through study completion an average of 1 year .
Timeframe: Asses the perivlance of cervical spine abnormalities in patient with Down syndrome of patients aged from 2 years up to 18 years ,using measure tool atlanoaxial instability in ct neck (ADI>3ml)and other mutliple measures ex(weight,height,eg.)