RecruitingNot Applicable

Predictors of Emergency Department Use in Frail Patients

Italy110 participantsStarted 2023-11-19

Plain-language summary

When admitted to the emergency department (ED), elderly non-autonomous patients show high risk of adverse health outcomes. The prompt identification of ED use risk factors in such population is hence needed. While cognitive impairment is a known clinical risk factor, biomarkers of most prevalent dementias have been scarcely investigated as possible ED use predictors. Within this context, this prospective study aims at exploring whether plasma phospho-tau181 and cerebrovascular burden can predict ED use at 6 months in elderly non-autonomous patients, irrespective of frailty.

Who can participate

Age range65 Years

SexALL

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Inclusion Criteria: * fluency in Italian language, * age higher than 64 years, * loss of autonomies of daily living as assessed by the Katz Activities of Daily Living or in the Lawton Instrumental Activities of Daily Living questionnaires, * having performed routinary blood exams in the 6 months prior to recruitment * having performed head neuroimaging feasable for cerebrovascular burden assessment, i.e., Magnetic Resonance Imaging (MRI) or computed tomography (CT), in the 6 months prior to recruitment. Exclusion Criteria: * withdrawal of the informed consent

What they're measuring

Emergency Department Use

Timeframe: Within 6 months from recruitment

Trial details

NCT IDNCT07259499

SponsorUniversity of Pisa

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-12-31

Contact for this trial

Francesco Turco, MD, PhD

+39-050992905 francesco.turco@phd.unipi.it

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