Dexmedetomidine Target Controlled infusion (TCI, Dyck model) effects on Neuromonitoring during Total Intravenous Anesthesia (TIVA) with Propofol and Remifentanil TCI (Eleveld model) has not been investigate yet. Authors aim to investigate its effect on Patient State index (PSi), the power spectrum EEG, the Analgesia Nociception Index (ANI) and pupillometry values during maintenance during TIVA-TCI with Propofol, Remifentanil and Dexmedetomidine.
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Effects of Dexmedetomidine on Patient State index (PSi) during stable Propofol - Remifentanil general anesthesia
Timeframe: PSi values and DexmedetomidineTarget Controlled Infusion (TCI) concentrations will be monitored during all the time of surgery
Effects of Dexmedetomidine on Electroencephalogram (EEG) power spectrum during stable Propofol - remifentanil general anesthesia
Timeframe: EEG power spectrum and DexmedetomidineTarget Controlled Infusion (TCI) concentrations will be monitored during all the time of surgery
Effects of Dexmedetomidine on Analgesia Nociception Index (ANI) during stable Propofol general anesthesia
Timeframe: ANI values and Sufentanil Target Controlled Infusion (TCI) concentrations will be monitored during all the time of surgery