Comparison of Dressing Materials of Donor Site of Split-thickness Skin Graft; Paraffin Mesh Gauze… (NCT07257991) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Comparison of Dressing Materials of Donor Site of Split-thickness Skin Graft; Paraffin Mesh Gauze vs Povidone-Iodine Foam at SMBB Institute of Trauma Karachi
82 participantsStarted 2026-01-01
Plain-language summary
The goal of this clinical trial is to learn if povidone-iodine foam dressing is better in achieving complete reepithelialization of donor site wounds after harvest of split-thickness skin graft as paraffin mesh gauze.
The main questions it aims to answer are:
Does povidone-iodine foam dressing promotes complete reepithelialization earlier in comparison? Which type of dressing will require fewer replacements? Which type of dressing material is associated with less pain?
Non-probability consecutive sampling method will be used and participants divided in two groups. Donor site wounds after split-thickness skin graft harvest will be dressed using two different dressing materials. Participants will be followed until complete epithelialization with change of dressing on follow-ups if required. Complete epithelialization is usually achieved within two weeks.
Who can participate
Age range
18 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Undergoing skin graft with donor site size between 25 to 200 cm2
Exclusion Criteria:'
* Patients wit history of disease impairing wound healing (Diabetes, Malignancy, Cancer, taking immunosuppressants)
* Pregnant or lactating females
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is comparing two specific dressings — paraffin mesh gauze and povidone-iodine foam — for the donor site wound after a split-thickness skin graft; which of these two dressings is my doctor already leaning toward using for me, and what is their reasoning?
2Since this trial isn't recruiting yet, how long might it be before I could even be considered for enrollment, and would waiting affect my treatment timeline or outcomes?
3The trial is measuring whether the donor site wound fully heals by day 14 — what does my doctor expect my own healing timeline to look like, and how does that compare to what this study is trying to find out?
4This trial is listed as Phase NA, which often means it's comparing existing standard treatments rather than testing something brand new — does that mean both dressings are already considered safe options, and what are the known risks or discomforts associated with each one for the donor site?
5If I don't join this trial, which dressing would my doctor use for my donor site wound, and is there any reason to think one option is already preferred based on current evidence?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Percentage of patients with complete reepithelialization at day 14
Timeframe: From the day of procedure till complete reepithelialization, nearly 14 days
Trial details
NCT IDNCT07257991
SponsorShaheed Mohtarma Benazir Bhutto Institue of Trauma