Active — Not RecruitingPhase 1

Evaluation of BH4 Responsiveness in Our PKU Patients

Egypt20 participantsStarted 2025-09-01

Plain-language summary

This study aims to evaluate BH4 responsiveness in our PKU patients and to correlate BH4 responsiveness with their genotype

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients were supplemented with phenylalanine a protein rich supplement based on milk protein, or an increase in natural protein intake) if phenylalanine was \< 400 μmol/l Exclusion Criteria: * if phenylalanine was less than 400 μmol/l

What they're measuring

• Serum phenylealanine level in patients after given tetrahydrobiopterin

Timeframe: Blood samples were taken at Hour = 0, 8, 16, 24 and 48

Trial details

NCT IDNCT07255599

SponsorSohag University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01-01

View on ClinicalTrials.gov More Phenylketonuria (PKU) trials