TerminatedNot Applicable

Gut Peptides and Bone Remodeling in Children With Neuromuscular Disorders

Stopped: Terminated since further recruitment proved difficult

Denmark3 participantsStarted 2023-03-24

Plain-language summary

Both GIP and GLP-2 reduce bone resorption (measured as CTX) in healthy adult individuals. In this study, we will investigate whether GIP and GLP-2 reduce CTX in children with spinal muscular atrophy, duchenne muscular dystrophy, or cerebral palsy.

Who can participate

Age range10 Years – 17 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: \- Diagnosis with Cerebral palsy (CP), Duchenne muscular dystrophy (DMD) or Spinal muscular atrophy (SMA) resulting in the need of a wheelchair Exclusion Criteria: * Use of anti-resorptive medication * Confounding illnesses * Pregnancy * Allergy towards the components given on the test days * Hgb\<6.5 mmol/L

What they're measuring

CTX

Timeframe: -10 to 240 minutes

Trial details

NCT IDNCT07254988

SponsorUniversity of Copenhagen

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-01

View on ClinicalTrials.gov More Spinal Muscular Atrophy (SMA) trials