SuspendedNot Applicable

Dietary Guidelines for Americans-Ultra Processed Study

Stopped: Waiting for administrative approval to start study.

United States79 participantsStarted 2026-12

Plain-language summary

The purpose of this research is to test how processing food can affect how one's body responds to it.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * BMI 18.5-34.9 kg/m2 * Systolic \<139 mm Hg and Diastolic \<90 mm Hg * Able to understand and sign the consent form * Have own transportation to the Grand Forks Human Nutrition Research Center * Not allergic to study foods or unwilling to eat them * Willing to comply with study demands * Able to read and understand English Exclusion Criteria: * Taking statins or medication to lower blood pressure, * Taking anti-inflammatory or anti-diabetes medications * Pregnant, lactating, or planning to become pregnant * Diagnosed with an eating disorder * Taking weight loss medications * Smoke or use other tobacco products, including e-cigarettes * Have overt hypothyroidism * Diagnosed with cancer * Exercise more than 30 minutes per day 2 or more days per week * Allergic to study foods * Express unwillingness to consume study foods at the screening appointment

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Mean difference in systolic and diastolic blood pressure from baseline

Timeframe: Week 0, Week 4

Trial details

NCT IDNCT07252037

SponsorUSDA Grand Forks Human Nutrition Research Center

Sponsor typeFED

Study typeINTERVENTIONAL

Primary completion2029-12

View on ClinicalTrials.gov More Overweight , Obesity trials

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.