Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery (NCT07251101) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery
South Korea58 participantsStarted 2026-05-02
Plain-language summary
This single-center study at CHA Ilsan Medical Center compares intraoperative hemodynamics between remimazolam- and propofol-based total intravenous anesthesia (TIVA) in patients undergoing robot-assisted gynecologic surgery requiring pneumoperitoneum and steep Trendelenburg positioning.
Who can participate
Age range
65 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Female patients \<65 years of age
* American Society of Anesthesiologists (ASA) physical status I-II
* Scheduled to undergo robotic hysterectomy under general anesthesia
Exclusion Criteria:
* Body mass index (BMI) \> 35 kg/m²
* Baseline hypotension (systolic blood pressure \<100 mmHg) or bradycardia (heart rate \<60 bpm)
* History of ischemic heart disease or cardiac conduction block
* Significant cardiopulmonary disease, including hypoxemia (SpO₂ \<90%), uncontrolled asthma, or chronic obstructive pulmonary disease (COPD)
* Use of inhalational anesthetics during anesthesia
* Conversion from robotic/laparoscopic surgery to open laparotomy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
MAP (Time-Weighted Average)
Timeframe: from induction start (first anesthetic administration) to operating room exit (transfer from OR), approximately up to 5 hours per participant.
Trial details
NCT IDNCT07251101
SponsorIlsan Cha hospital
Sponsor typeOTHER
Study typeINTERVENTIONAL
Primary completion2027-10-31
Contact for this trial
Joohyun Lee Assistant Professor, Dept. of Anesthesiology and Pain Medicine, MD