Not Yet RecruitingNot Applicable

Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery

South Korea58 participantsStarted 2026-05-02

Plain-language summary

This single-center study at CHA Ilsan Medical Center compares intraoperative hemodynamics between remimazolam- and propofol-based total intravenous anesthesia (TIVA) in patients undergoing robot-assisted gynecologic surgery requiring pneumoperitoneum and steep Trendelenburg positioning.

Who can participate

Age range65 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female patients \<65 years of age * American Society of Anesthesiologists (ASA) physical status I-II * Scheduled to undergo robotic hysterectomy under general anesthesia Exclusion Criteria: * Body mass index (BMI) \> 35 kg/m² * Baseline hypotension (systolic blood pressure \<100 mmHg) or bradycardia (heart rate \<60 bpm) * History of ischemic heart disease or cardiac conduction block * Significant cardiopulmonary disease, including hypoxemia (SpO₂ \<90%), uncontrolled asthma, or chronic obstructive pulmonary disease (COPD) * Use of inhalational anesthetics during anesthesia * Conversion from robotic/laparoscopic surgery to open laparotomy

What they're measuring

MAP (Time-Weighted Average)

Timeframe: from induction start (first anesthetic administration) to operating room exit (transfer from OR), approximately up to 5 hours per participant.

Trial details

NCT IDNCT07251101

SponsorIlsan Cha hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-10-31

Contact for this trial

Joohyun Lee Assistant Professor, Dept. of Anesthesiology and Pain Medicine, MD

+82-31-782-8415 hightothesky1004@gmail.com

View on ClinicalTrials.gov More Anesthesia, Intravenous trials