CompletedNot Applicable

Comparison of Fractionated Versus Bolus Administration of Different Doses of Hyperbaric Bupivacaine Combined With Opioids in Spinal Anesthesia for Caesarean Section

Ukraine99 participantsStarted 2024-06-30

Plain-language summary

This study aimed to compare the effectiveness and safety of fractionated versus bolus administration of different doses of hyperbaric bupivacaine (0.06 and 0.07 mg/cm height) combined with opioids in spinal anesthesia for cesarean section, with detailed evaluation of maternal hemodynamic effects, block characteristics and side effects.

Who can participate

Age range18 Years – 50 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * singleton full-term pregnancy scheduled for cesarean section under spinal anesthesia * ASA physical status II-III * age 18-50 years * height from 140 to 180 cm * body weight from 40 to 130 kg Exclusion Criteria: * patient refusal * contraindications to spinal anesthesia * allergy to amide-type local anesthetics

What they're measuring

Hemodynamic Stability (systolic, diastolic and mean arterial pressure, heart rate)

Timeframe: Perioperative/Periprocedural - before spinal anesthesia and then during the cesarean section until its completion

Trial details

NCT IDNCT07249814

SponsorBogomolets National Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-15

View on ClinicalTrials.gov More Spinal Anesthesia for Cesarean Section trials