Type 2 Diabetes and Associated Factors in Mexico (NCT07248891) | Clinical Trial Compass
By InvitationNot Applicable
Type 2 Diabetes and Associated Factors in Mexico
Mexico1,000 participantsStarted 2025-04-01
Plain-language summary
The goal of this observational cross-sectional multicenter study is to identify clinical, lifestyle, metabolic, inflammatory, and genetic factors associated with glycemic control and complications of Type 2 Diabetes (T2D) in adult patients in Mexico.
The main questions it aims to answer are:
Which molecular and clinical factors are associated with poor glycemic control (HbA1c \> 7%)?
Which factors are linked to the presence of diabetic nephropathy (GFR \< 60 mL/min/1.73 m²)?
Participants:
Provide informed consent and clinical history.
Undergo a clinical and physical evaluation (including six-minute walk test).
Complete lifestyle, dietary, and therapeutic adherence questionnaires.
Provide blood samples for biochemical, inflammatory, and transcriptomic (RNA-Seq) analysis.
Researchers integrate clinical, biochemical, and transcriptomic data using statistical modeling to identify a characteristic molecular fingerprint of poor metabolic control and diabetes-related complications.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adults 18 years of age or older.
* Established diagnosis of Type 2 Diabetes Mellitus (T2D).
* Patients receiving care at Family Medicine Units in Coahuila, Jalisco, or Veracruz.
* Willingness to voluntarily participate in the study.
* Ability to understand the study procedures and provide written informed consent.
Exclusion Criteria:
* Pregnant or lactating mother
* Current use of steroids
* Concomitant illness with inflammatory or autoimmune component (rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, psoriatic arthritis, gout).
* Tobacco use (in the last 3 months).
* History of cerebrovascular disease, heart failure or kidney failure that required hospitalization in the previous month.
* History of infection in the previous 10 days (respiratory tract infection, gastroenteritis, urinary tract infection, soft tissue infection).
* Severe obesity with BMI \> 40 kg/m2. History of bariatric surgery.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Glycemic control (% HbA1c)
Timeframe: At baseline (single cross-sectional assessment).
2
Diabetic Nephropathy (eGFR)
Timeframe: At baseline (single cross-sectional assessment).
Trial details
NCT IDNCT07248891
SponsorCoordinación de Investigación en Salud, Mexico