Not Yet RecruitingNot Applicable

Start Taking Action for Tuberculosis in Kids

7,920 participantsStarted 2026-03-01

Plain-language summary

Start4Kids: Evaluating the performance, feasibility, acceptability and cost effectiveness of computer-aided detection (CAD) of chest X-ray (CXR) and concurrent testing using novel diagnostics and non-sputum specimens for childhood tuberculosis (TB) in Bangladesh, Cameroon, Kenya and Viet Nam.

Who can participate

Age range0 Years – 15 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Age 14 and below on the day of assessment
✓. Fulfils the criteria of presumptive TB according to the definition 10.1 of the protocol, or TB associated risk factors according to the definition 10.2. of the protocol
✓. Diagnosed with TB disease

Exclusion criteria

✕. On treatment for TB disease at the time of evaluation
✕. Parent or guardian does not allow the child to participate in the study or declines to sign the ICF.
✕. The child does not wish to participate in the study or declines to sign the Assent Form (where applicable)

What they're measuring

The diagnostic accuracy (sensitivity, specificity, positive and negative predictive values) will be estimated for all individual tests and modelled combinations to evaluate a concurrent testing strategy.

Timeframe: 1 Year

Trial details

NCT IDNCT07248423

SponsorLiverpool School of Tropical Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-03-01

View on ClinicalTrials.gov More TB - Tuberculosis trials