Epidemiological Study of Treatment Approaches in AChR-Antibody Positive Generalized Myasthenia Gr… (NCT07247279) | Clinical Trial Compass
RecruitingNot Applicable
Epidemiological Study of Treatment Approaches in AChR-Antibody Positive Generalized Myasthenia Gravis in Russia
Russia450 participantsStarted 2025-12-23
Plain-language summary
This is a multicenter, non-interventional, retrospective-prospective, single-arm observational study designed to describe real-world treatment approaches and clinical outcomes among adults with acetylcholine receptor (AChR) antibody-positive generalized myasthenia gravis (gMG) in routine clinical practice in Russia.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Adults (≥18 years) diagnosed with generalized MG positive for acetylcholine receptor (AChR) antibodies.
. Provision of signed and dated written informed consent.
Exclusion criteria
. Participants currently enrolled in clinical studies for treatment of gMG.
. Ocular MG only.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Age at baseline (years)
Timeframe: Baseline (Month 0; at informed consent and enrollment)
2
Age at gMG diagnosis (years)
Timeframe: Baseline (retrospective abstraction at Month 0)
3
Sex and ethnicity distribution
Timeframe: Baseline (Month 0)
4
Body Mass Index (BMI)
Timeframe: Baseline (Month 0; last available measurements closest to ICF signing)
5
Disease duration (days)
Timeframe: Baseline (Month 0)
6
Clinical symptom profile of gMG
Timeframe: Baseline (Month 0)
7
Comorbidity profile
Timeframe: Baseline (Month 0)
8
Number and proportion of patients with gMG-related hospitalizations