Multicentre Study on the Impact of Transmucosal Abutment Surface Characteristics on Peri-implant … (NCT07246499) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Multicentre Study on the Impact of Transmucosal Abutment Surface Characteristics on Peri-implant Tissues.
Spain25 participantsStarted 2025-11-01
Plain-language summary
The main objective of the study is to perform proteomic adsorption analysis on machined (grey) and anodised (pink) surfaces and compared them. The aim is to evaluate the regenerative potential involving improvement in the healing of peri-implant soft tissues in patients with dental implants. This surgery is indicated in healthy patients when they lost their teeth.
The main question it seeks to answer is:
\- In dental abutments, is anodised surface more effective than machined surface in terms of the degree of healing?
The study will include patients who need this type of surgery and meet specific clinical criteria. Each patient will have one of the two dental abutments applied as part of the standard surgical procedure. Subsequently, participants will undergo clinical and proteomic follow-up assessments to evaluate the progress and extent of peri-implant tissue healing over a three-months period.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Number of missing teeth and, therefore, number of implants required.
* A minimum of 4 implants, either single or bridges, must always be used in order to place 2 machined abutments and 2 anodised abutments.
* Sufficient bone dimensions for a minimum implant diameter of 3.5-4 mm and length of 6-8 mm, without prior bone regeneration.
* Patients who require indirect breast lift simultaneously with implant placement may be included in the study.
* Minimum keratinised mucosa dimension of 1.5-2.0 mm in all directions.
* Previous healthy bone condition for 3 months without infection.
* Periodontal health with no history of periodontitis (Silness and Löe plaque index, bleeding on probing (BOP) \< 3 mm).
Exclusion Criteria:
* Patients unable to complete follow- up.
* Implant failures.
* Contamination of the sample during transfer from the abutment to the test tube.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Proteomic analysis of peri-implant tissue healing.
Timeframe: 7 days and 3 months after abutment placement.