Biofilm Formation and Antifungal Resistance in Candida Species (NCT07245563) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Biofilm Formation and Antifungal Resistance in Candida Species
300 participantsStarted 2025-12-20
Plain-language summary
1. To determine the susceptibility pattern of our local isolated Candida strains which is essential for optimal management of fungal infection.
2. Detection of biofilm formation by conventional and molecular methods
3. Comparison between C. albicans and non-albicans in the prevalence of biofilm formation and biofilm -forming genes
4. Find the association between antifungal resistance and biofilm formation in candida strains isolated from patients
5. Determination of clinical factors associated with occurrence of infections.
Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Eligible participants in the study were those with invasive infection and had one or more of this criteria :
oSuppressed general body immunity.
oSuppressed local body immunity as a result of trauma or invasive procedures.
oResistant to antibiotic therapy.
oNegative samples for bacterial examination and culture.
Critical life threatening infect
Exclusion Criteria:
* Patients who received antifungal therapy within 3 days prior to sample collection.
* Resistant to antibiotic therapy.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
To asses the prevalence of candida species as a cause of infection in patient in hematology intinsive care unit
Timeframe: 1 year
2
To asses the prevalence of genes responsible for biofilm formation in different candida species