A Translational Study for Phenotyping and Endotyping Chinese Patients With NCFBE

Inclusion Criteria: Healthy control cohort: · Age ≥30 years Bronchiectasis cohort: * Capable of giving signed informed consent. * Participant must be ≥18 years of age, at the time of signing the ICF. * Able to perform acceptable lung function testing according to ATS/ERS 2019 acceptability criteria. * Able and willing to comply with the requirements of the protocol including ability to read, write, be fluent in the translated language of all participants facing questionnaires used at center, and use electronic devices (e.g. FENO and spirometry). * Documented physician-diagnosed bronchiectasis: with a clinical history consistent with bronchiectasis (chronic cough and daily sputum production etc.) and having performed chest HRCT indicating bronchiectasis. * Remaining clinically stable upon recruitment. Patients with exacerbations are allowed to be enrolled into the study at least 4 weeks after the end of exacerbations. If a patient experiencing exacerbation and directly enters the exacerbation visit, the patient is required to come to the study site for baseline visit (after confirming that all inclusion/exclusion criteria are met) within 4 weeks /+ 3 days after the end of exacerbation Exclusion Criteria: Healthy control cohort: * Any respiratory diagnosis (asthma, COPD, bronchiectasis, pulmonary fibrosis or any other chronic respiratory condition requiring regular treatment). * Inflammatory conditions including rheumatoid arthritis, inflammatory bowel disease, any other…