Comparison of Two Dosing Regimens of Intravenous Ketorolac for Post-Cesarean Pain Control (NCT07244757) | Clinical Trial Compass
CompletedNot Applicable
Comparison of Two Dosing Regimens of Intravenous Ketorolac for Post-Cesarean Pain Control
Egypt125 participantsStarted 2025-12-01
Plain-language summary
we aim to compare the analgesic efficacy of two intravenous ketorolac dosing regimens as part of a multimodal analgesic protocol that includes local wound infiltration for postoperative pain management after elective cesarean delivery.
Who can participate
Age range
18 Years – 35 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* full-term, singleton, pregnant women,
* aged 18-35 years,
* scheduled for elective cesarean delivery under spinal anesthesia
Exclusion Criteria:
* American Society of Anesthesiologists (ASA) physical class III or more
* multiple gestation. Patients with a history of allergy to any of the study drugs,
* renal impairment,
* gastrointestinal bleeding or ulceration
* inflammatory bowel disease,
* chronic pain or regular opioid use.
* Inability to comprehend the numeric pain scale (NRS) or the ObsQoR-11 score
* requirement for conversion to general anesthesia after spinal anesthesia
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compared two different dosing regimens of IV ketorolac for pain after a C-section — can you tell me what those two dosing approaches were, and whether the results showed one was meaningfully better at reducing pain at rest?
2Since this study used a numeric rating scale at rest as its main measure, does that mean we know less about how well each ketorolac dose controlled pain during movement or activity, like getting up to care for a newborn?
3Ketorolac is an NSAID — are there any situations specific to my health history, like kidney function or bleeding risk, that might make one dosing regimen safer for me than the other after a C-section?
4Now that this trial is completed, has the evidence from it influenced how your practice approaches ketorolac dosing after cesarean deliveries, or is the standard approach here still different?
5Are there other pain management options after a C-section that I should weigh alongside what this ketorolac study found, especially if I plan to breastfeed?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.