Ejaculatory Behavior and Seminal Vesicle Size During Radical Prostatectomy (NCT07243795) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Ejaculatory Behavior and Seminal Vesicle Size During Radical Prostatectomy
Taiwan40 participantsStarted 2025-12-01
Plain-language summary
The goal of this clinical trial is to learn if recent ejaculation or abstinence before surgery affects seminal vesicle size and dissection-related surgical factors in adult men with prostate cancer undergoing radical prostatectomy. The main questions it aims to answer are:
Does ejaculation within 36 hours before surgery reduce seminal vesicle size compared to abstinence of 72 hours or more?
Does seminal vesicle size affect the ease or difficulty of surgical dissection during radical prostatectomy?
Researchers will compare an ejaculation group to an abstinence group to see if seminal vesicle volume and intraoperative surgical parameters differ between them.
Participants will:
Follow specific instructions to either ejaculate or abstain before surgery
Undergo a transrectal ultrasound (TRUS) to measure seminal vesicle size after anesthesia but before surgery
Have their surgical dissection time and difficulty rated by the operating surgeon
Who can participate
Age range
18 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male patients aged 18 years or older
* Histologically confirmed prostate cancer
* Scheduled for radical prostatectomy
* Able and willing to comply with assigned ejaculation or abstinence protocol
* Willing to complete preoperative questionnaire
* Willing to undergo transrectal ultrasound (TRUS) 12-14 hours before surgery
* Able to understand and sign informed consent
Exclusion Criteria:
* Prior bilateral seminal vesicle resection or congenital absence of seminal vesicles
* Anatomical abnormalities preventing SV identification
* Hormone therapy within 6 months before surgery
* Inability to recall ejaculation history in the past 3 days
* Inability to follow behavioral instructions or TRUS protocol
* Severe anorectal disease or history of anorectal surgery preventing TRUS
* Cognitive or psychiatric conditions impairing informed consent
* Incomplete data or poor-quality imaging
* Prior prostate cancer treatment
* Belonging to a vulnerable population (e.g., minors, prisoners, pregnant individuals, cognitively impaired, etc.)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Seminal vesicle volume measured by preoperative transrectal ultrasound (TRUS)
Timeframe: 12-14 hours before surgery (afternoon prior to operation)