Rice Bran Supplementation for Radiation-Induced Oral Mucositis in Head and Neck Cancer (NCT07242859) | Clinical Trial Compass
RecruitingNot Applicable
Rice Bran Supplementation for Radiation-Induced Oral Mucositis in Head and Neck Cancer
Egypt80 participantsStarted 2023-01-15
Plain-language summary
This study aims to find out if taking rice bran supplements can help reduce the painful mouth sores (oral mucositis) that often occur in patients with head and neck cancer who receive radiation therapy. The trial will include adult patients undergoing radiation treatment. Participants will be given rice bran supplements during their therapy to see if it can lessen these side effects and improve their overall quality of life.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male or female patients of age 18 years old tor more
* Patients with squamous cell carcinomas without metastases of other non-head and non-neck tumors.
* Patients undergoing radiotherapy with an ECOG performance status of 0, 1, or 2
* Patients who will receive IMRT delivered as radical or adjuvant therapy with or without concurrent chemotherapy
* Ready to provide written informed consent
Exclusion Criteria:
* Receiving any other approved or investigational anti-cancer agent than those specified in this study.
* Pregnant or breastfeeding female patients
* Patients who have oral lesions unrelated to treatment or cancer,
* Patients who are on drugs that could cause oral lesions or are using anticoagulants.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of grade ≥ 3 mucositis .
Timeframe: From the start of radiation therapy until 2 weeks after completion of treatment (approximately 8 weeks)