Not Yet RecruitingNot Applicable

Regional Analgesia Techniques for Laparoscopic Cholecystectomy

Turkey (Türkiye)147 participantsStarted 2025-12-01

Plain-language summary

This single-center, prospective, randomized controlled trial aims to compare the effects of paravertebral block (PVB), external oblique intercostal (EOI) block, and intravenous patient-controlled analgesia (PCA) with tramadol on postoperative pain and opioid consumption in patients undergoing elective laparoscopic cholecystectomy. The primary endpoint is total tramadol consumption within 24 hours postoperatively. Secondary outcomes include pain scores, additional analgesic use, incidence of nausea/vomiting, mobilization time, and length of hospital stay.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age between 18 and 65 years * Scheduled for elective laparoscopic cholecystectomy under general anesthesia * ASA physical status I-III * Able to understand the study procedure and provide informed consent Exclusion Criteria: Patient refusal or inability to provide informed consent Allergy or contraindication to local anesthetics, tramadol, or study medications Coagulopathy or current anticoagulant therapy Local infection at the planned block injection site Severe hepatic or renal impairment Chronic opioid use or opioid dependence Neurological or psychiatric disorders affecting pain perception or communication Pregnancy or breastfeeding Body mass index (BMI) \> 35 kg/m² Conversion to open cholecystectomy during surgery

What they're measuring

24-hour postoperative tramadol consumption

Timeframe: Within the first 24 hours after surgery.

Trial details

NCT IDNCT07241949

SponsorCukurova University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-01

Contact for this trial

Nurefsan Sadikoglu, MD

+(90) 538 926 2414 nurefsansadikoglu@gmail.com