Progressive supranuclear palsy (PSP), mild cognitive impairment with Lewy bodies (MCI-LB), and Dementia with Lewy Bodies (DLB) are severe neurodegenerative diseases that cause significant motor impairment impacting daily function. Researchers at BioSensics, Johns Hopkins School of Medicine, Massachusetts General Hospital and their collaborators aim to conduct an analytical and clinical validation of wearable-based digital health technologies for monitoring upper and lower limb function in PSP, MCI-LB and DLB that could enable frequent, at-home monitoring and be incorporated into future clinical trials.
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2-Minute Walk Test (2MWT)
Timeframe: Baseline.
Timed Up & Go Test (TUG)
Timeframe: Baseline.
5-times Sit-to-Stand Test (5xSTS)
Timeframe: Baseline.
Box and Block test (BBT)
Timeframe: Baseline.
9-Hole Peg Test (9HPT)
Timeframe: Baseline
Physical Activity Monitoring
Timeframe: 14 days
Gait Monitoring
Timeframe: 14 days
Hand Function Monitoring
Timeframe: 14 days