This project serves to continue a community-based initiative, known as the Kenya Mother-Daughter Cervical Cancer Eradication Project, or the Mother-Daughter Project (MDP), in the Webuye region of Western Kenya. The MDP project, since its initiation in 2018, has sought to develop a framework for the eradication of cervical cancer through effective screening of adult women and through the vaccination of female children. This project specifically aims to collect additional data on the ability for HR-HPV testing to detect premalignant lesions of the cervix, especially in HIV-infected women, to investigate and identify barriers leading to non-participation in previous MDP efforts, and to examine factors associated with the immune response to HPV vaccination among rural Kenyan girls.
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Detection of CIN2/3
Timeframe: Baseline
Local knowledge and attitudes
Timeframe: Baseline and after HPV vaccination of daughters is complete (assessed 2 weeks after second vaccine)
Barriers to participation
Timeframe: During a one-time interview
Factors that influence immunity to the HPV vaccine
Timeframe: 24 months after second HPV vaccine