Not Yet RecruitingPhase 4

Beta-lactam Plus Levofloxacin to Enhance Therapy in Streptococcal Septicemia

Thailand165 participantsStarted 2026-01-01

Plain-language summary

A double-blind randomized controlled trial comparing beta-lactam plus levofloxacin versus beta-lactam monotherapy for the treatment of Streptococcal bacteremia

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Adults age\>18 years
✓. Blood culture positive for Streptococcus (\<72 hours before enrollment)
✓. Receiving or having plan of receiving beta-lactam therapy

Exclusion criteria

✕. Known allergy to beta-lactam or fluroquinolone antibiotics
✕. Pregnancy or lactating mother
✕. EKG with QT prolongation
✕. Diagnosis of infective endocarditis

What they're measuring

Composite endpointof unfavorable outcome

Timeframe: 28 days after the onset of infection

Trial details

NCT IDNCT07240077

SponsorMahidol University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-12-31

Contact for this trial

Pinyo Rattanaumpawan

66897778176 pinyo.rat@mahidol.ac.th

View on ClinicalTrials.gov More Bacteremia trials