Comparison Between Modified Periosteal Inhibition (MPI) and Flapless Immediate Implant Placement (NCT07238738) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Comparison Between Modified Periosteal Inhibition (MPI) and Flapless Immediate Implant Placement
Egypt30 participantsStarted 2025-12-01
Plain-language summary
To clinically and radiographically assess the impact of the modified periosteal inhibition (MPI) technique, applied during immediate post-extraction implant placement, on alveolar bone dimensional changes, in comparison to the conventional flapless immediate implant approach.
Who can participate
Age range
20 Years – 50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patient's age ranges between 20 and 50 years including both genders.
* General good health (American Society of Anesthesiologists I-II).
* Presence of one hopeless non-restorable tooth requiring extraction at the posterior region.
* Adequate amount of palatal bone and basal bone (≥ 3 mm) to engage the immediately placed implants.
* Adequate keratinized soft tissue.
* Thick gingival phenotype (˃ 1.5 mm).
* Thin buccal bone plate or presence of fenestration.
* Favorable pattern of occlusion.
* Patient who is able to understand and sign a written consent.
Exclusion Criteria:
* Pregnancy or lactating females.
* Untreated periodontitis.
* Acute dentoalveolar infection.
* Complete absence of buccal bone plate.
* Osteometabolic disease.
* Chemotherapy or radiation therapy history of the neck-head area within the past 12 months.
* Heavy smokers (\>20 cigarettes/per day) according to WHO.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Radiographic evaluation of horizontal and vertical dimensional changes of the alveolar bone placement by using cone beam computed tomography (CBCT).
Timeframe: Baseline, 6 months, 12 months after the implant placement