Assessment of the Efficacy of Topical Ketoconazole 2% Cream in Comparison With Topical Retinoids in the Treatment of Mild Comedonal and Papulopustular Acne

Inclusion Criteria: * Patients with mild comedonal or papulopustular acne with a GEA score from 1-2 on the face. * Both sexes. * Age: adolescents and adults. * Skin type 3 and 4. Exclusion Criteria: * • Patients using, will use during the study, or discontinued less than 4 weeks before study baseline, prescribed or over-the counter topical therapies for the treatment of acne. * Patients using, will use during the study, or discontinued less than 4 weeks before study baseline, any facial procedures such as chemical peel, laser treatment or depilation in area of treatment application (except eyebrow shaping). * Patients with outdoor occupation, exposed to sun and heat. * Patients using, will use during study any cosmoceuticals. * Patients using, will use during the study, or discontinued less than 12 weeks before study baseline, systemic therapies for the treatment of acne or any other systemic treatments. * Patients with other special types of acne or conditions presenting with acne/acneiform eruption. * Irregular menstrual cycles or clinically suspected polycystic ovarian syndrome. * Patients with other facial rashes preventing the accurate assessment. * Known or suspected allergy to ingredients. * Pregnancy or lactation.