Active — Not RecruitingNot Applicable

CVL Risk After Severe Glaucoma Surgery

South Korea523 participantsStarted 2024-11-27

Plain-language summary

This retrospective cohort study analyzes risk factors for central visual loss (CVL) after severe-stage glaucoma surgery. The primary hypothesis is that 1) visual prognosis is determined primarily by early postoperative intraocular pressure (IOP) stability rather than surgical choice, and 2) the nature of risk (hypotony vs hypertension) is modified by baseline visual reserve. We analyzed outcomes in 523 patients with severe-stage glaucoma who underwent trabeculectomy or Ahmed glaucoma valve (AGV) implantation, focusing on the dichotomous risk profile stratified by baseline visual acuity.

Who can participate

SexALL

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Inclusion Criteria: * 1\. Patients who underwent trabeculectomy or Ahmed glaucoma valve implantation at Yonsei Medical Center between January 2005 and October 2024. 2\. Glaucoma patients who underwent static quantitative perimetry (visual field test) before and after surgery. 3\. Patients with a preoperative Mean Deviation (MD) of ≤ -20 dB. Exclusion Criteria: * 1\. Patients who were unable to undergo visual field testing due to poor preoperative visual acuity. 2\. Patients with central visual field defects caused by retinal or neurological diseases other than glaucoma. 3\. Patients with false-positive or false-negative responses ≥33% on visual field testing.

What they're measuring

Central Visual Loss (CVL) at 3 months postoperatively

Timeframe: At 3 months postoperatively

Trial details

NCT IDNCT07237555

SponsorGangnam Severance Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-11-26

View on ClinicalTrials.gov More Severe-stage Glaucoma (Mean Deviation ≤ -20 dB) trials