Not Yet RecruitingNot Applicable

Usage of Glucose Fluctuations as a Prognostic Marker in Septic Shock Patients

105 participantsStarted 2026-12-01

Plain-language summary

To determine whether glucose fluctuations prior to antibiotic administration are associated with sepsis severity and poor clinical outcomes. * To assess if the time to Glycemic Normalization after Antibiotic Initiation can be used as an Early Prognostic Indicator in Sepsis. * To evaluate the Glycemic Shock Index (GSI) as a Combined Marker of Hemodynamic and Metabolic Stress in ICU Sepsis Patients.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adults ≥18 years admitted to ICU with suspected or confirmed sepsis. * Sepsis diagnosed using Sepsis-3 criteria (infection + SOFA ≥2). * At least 2 blood glucose readings within 6 hours prior to the first dose of antibiotics. * at least 3 after starting antibiotics within 24 hours. Exclusion Criteria: * Steroid use in prior 48 hours. * DKA, HHS, or acute pancreatitis. * Incomplete glucose data or delayed documentation.

What they're measuring

ICU mortality

Timeframe: Baseline

AKI

Timeframe: Baseline

Trial details

NCT IDNCT07234526

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2028-12-01

Contact for this trial

Shaban N S Tamer, Bachelor degree of medicin

+201286606934 shabaan2021@icloud.com

View on ClinicalTrials.gov More Glucose Fluctuations in Sepsis trials