CompletedNot Applicable

Stimulation of the Dentate Nucleus of the Cerebellum for the Treatment of Refractory Spasticity With or Without Dystonia

20 participantsStarted 2016-04-01

Plain-language summary

Electrical stimulation (DBS) through electrodes implanted in the dentate nucleus of the cerebellum for the treatment of tremor intractable with medication, dystonia due to cerebrovascular disease (stroke), sequelae of traumatic brain injury, and ataxia (a disease that causes incoordination of movements). Use of advanced magnetic resonance imaging techniques and recording of nerve cell activity in this nucleus

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Age 18 or older
✓. Clinical diagnosis of cerebellar syndrome resulting from stroke and spinocerebellar degeneration, intractable tremor, primary or secondary dystonia, refractory to drug and physiotherapy treatment;
✓. Signed the term of free and informed consent

Exclusion criteria

✕. Age under 18 years;
✕. Presence of severe anatomical deformities in the cerebellum and/or brainstem;

What they're measuring

DSB in the dentate nucleus

Timeframe: From enrollment to the end of treatment at 16 weeks

Trial details

NCT IDNCT07231302

SponsorKleber Paiva Duarte

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-11-30

View on ClinicalTrials.gov More Ataxia - Other trials