The goal of the study is to examine how two key subregions of the human thalamus (ANT and PLV) are connected with other brain structures (Aim 1), how seizures involve the two thalamic subregions differently and how the map of cortico-thalamic ictal propagation matches the intrinsic connectivity maps identified in the same individuals (Aim 2), and the effect of ANT and PLV stimulations on memory formation (Aim 3).
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Cerebro-cerebral evoked potentials
Timeframe: During experiment up to 2 weeks
fMRI BOLD activity
Timeframe: During experiment up to 2 weeks
Epileptogenicity Index (EI)
Timeframe: During experiment up to 2 weeks
Seizure propagation
Timeframe: During experiment up to 2 weeks
Coordinated activity across HPC and ANT
Timeframe: During experiment up to 2 weeks
Cognitive task performance
Timeframe: During experiment up to 2 weeks