CompletedPhase 1

Pharmacokinetic Interaction Trial of Clofutriben With Midazolam and Prednisolone

United States16 participantsStarted 2025-10-03

Plain-language summary

Drug: 2 single oral doses of midazolam, 2 single oral doses of prednisolone , and clofutriben once daily for 16 days.

Who can participate

Age range18 Years – 75 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male or female participants aged 18 to 75 years of age, * Body mass index of 18 to 35 kg/m2, * Taking no medications, * Are considered by the investigator to be in good general health. Exclusion Criteria: * In the opinion of the investigator, the participant is not suitable for entry into the trial or has any contraindication to midazolam or prednisolone.

What they're measuring

Cmax of midazolam.

Timeframe: 24 hours from dose

AUC0-t of midazolam

Timeframe: 24 hours from dose

Trial details

NCT IDNCT07226635

SponsorSparrow Pharmaceuticals

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2025-12-16

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