Not Yet RecruitingPhase 2

Dietary Interventions to Reduce Ultra-Processed Food Intake

60 participantsStarted 2026-02

Plain-language summary

The DISRUPT clinical trial will test two different 2-month programs to help adults with overweight/obesity (N=60) reduce their intake of ultra-processed foods (UPFs). Participants will be randomly assigned to receive standard dietary change strategies, cognitive dissonance strategies that engage them in activism against the UPF industry, or both. All participants will attend an introductory educational workshop about UPFs. If they are assigned to receive one or more of these strategies, they will attend weekly group sessions with the relevant intervention content for 7 more weeks. Groups will be held virtually.

Who can participate

Age range18 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Ages 18-70 years old * BMI \>25 and \<50 kg/m2 * Wish to reduce their UPF intake * Consume at least 2 UPF items per day and at least 4 distinct UPF items per week Exclusion Criteria: * Have ever been diagnosed with anorexia nervosa or bulimia nervosa * Are using medications known to influence eating behavior and/or weight (e.g., semaglutide) * Currently using insulin * History of bariatric surgery * Current pregnancy or planning to become pregnant during the study period

What they're measuring

Ultra-Processed Food Intake

Timeframe: Baseline, Post-Treatment (2 months)

Trial details

NCT IDNCT07226336

SponsorOregon Research Institute

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-08

Contact for this trial

Charlotte Hagerman, PhD

(609) 676-5816 chagerman@ori.org

View on ClinicalTrials.gov More Ultra-Processed Food Intake trials