Clinical Study to Evaluate the Tooth Whitening Efficacy of a New NextGen In-office Whitening System (NCT07225478) | Clinical Trial Compass
CompletedPhase 3
Clinical Study to Evaluate the Tooth Whitening Efficacy of a New NextGen In-office Whitening System
United States180 participantsStarted 2025-10-31
Plain-language summary
The goal of this clinical study is to evaluate how well a new in-office whitening system works to whiten teeth compared to some other commercially available in-office whitening systems.
Who can participate
Age range18 Years – 70 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Signed Informed Consent Form
* Male and female subjects aged 18-70 years, inclusive;
* Good general health and good oral health based on the opinion of the study investigator;
* All maxillary natural anterior teeth (teeth #6 through #11) must be present;
* Availability for the duration of the study;
* Minimum average Vita Extended Bleachedguide 3D-Master shade score of 17 ≥ or darker.
Exclusion Criteria:
* Presence of orthodontic appliances and/or any anterior tooth with a prosthetic crown, veneer, or deemed non-vital;
* Obvious signs of periodontal disease, rampant caries, or any condition that the dental examiner considers exclusionary from the study.
* Five or more carious lesions requiring immediate care.
* Concurrent participation in another oral clinical study.
* Self-reported pregnant and/or lactating women.
* History of allergies or sensitivity to tooth whitening products, hydrogen peroxide, personal care consumer products, or their ingredients;
* Restorations on the teeth to be scored which may interfere with scoring procedures.
* Have used professional whitening products within one (1) year and/or had dental prophylaxis (professional dental cleaning) within thirty (30) days prior to the start of the study.
What they're measuring
1
Whitening Improvements
Timeframe: Immediately after whitening and 1 week later.