Motor-Cognitive Training for Motoric Cognitive Risk Syndrome (NCT07223905) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Motor-Cognitive Training for Motoric Cognitive Risk Syndrome
United States10 participantsStarted 2026-03-10
Plain-language summary
The goal of this clinical trial is to investigate if combined motor-cognitive training can improve motor and cognitive symptoms in older adults with motoric cognitive risk syndrome. The main questions it aims to answer are:
* Does motor-cognitive training using a virtual reality treadmill improve gait speed?
* Does motor-cognitive training using a virtual reality treadmill improve cognitive functions?
Researchers will compare virtual reality treadmill training with treadmill training to see if virtual reality treadmill training works to improve motor and cognitive functions in older adults at risk of dementia
Participants will
* Complete 18 sessions (1 hour, 3x/week, 6 weeks) of either virtual reality treadmill training or treadmill training
* Complete a pre- and post-training assessment
* Wear an activity sensor for seven days prior to the pre-training assessment and for seven days after the post-training assessment.
Who can participate
Age range
65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age ≥ 65
* English speaking
* Normal cognition (CDR=0)
* Meet MCR criteria
* Voluntary consent
Exclusion Criteria:
* Major chronic unstable disease or neurological condition (e.g., seizures)
* Diagnosed dementia
* Active psychiatric conditions
* Musculoskeletal conditions that affect walking for more than 2 minutes
* Severe visual or hearing impairments
* Sedating drugs (new use of narcotics or anxiolytics within the past month or chronic use that causes sedation)
* Currently engaged in other non-pharmacological interventions to improve cognition or walking
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Dual-task gait speed
Timeframe: From enrollment to the end of treatment at 6 weeks
2
Cognition
Timeframe: From enrollment to the end of treatment at 6 weeks
3
Gait speed
Timeframe: From enrollment to the end of treatment at 6 weeks
4
Cognitive complaints
Timeframe: From enrollment to the end of treatment at 6 weeks